|
KMID : 0869220230270010016
|
|
Journal of Korean Geriatric Psychiatry
2023 Volume.27 No. 1 p.16 ~ p.22
|
|
|
Differences in White Matter Hyperintensity in Elderly Veterans With and Without Post-Traumatic Stress Disorder
|
|
Lee Eun-Young
Bae Hee-Won
Lee Seung-Hoon
Choi Jin-Hee
Choi Ha-Yun
|
|
|
Abstract
|
|
|
Objective: Exposure to stressful events is associated with the progression of white matter hyperintensity (WMH). The purpose of this study was to determine the difference in WMH depending on the presence of Post-traumatic stress disorder (PTSD).
Methods: The patients who underwent brain magnetic resonance imaging and clinician-administered PTSD scale (CAPS) at the Veteran Health Service Medical Center were reviewed retrospectively. WMH were evaluated using the Fazekas scale. The patients with PTSD (n=51; age 66.25±10.43 years) were compared with patients exposed to trauma without PTSD (n=67; age 69.45±10.44 years).
Results: The scores of Beck Depression Scale, Beck Anxiety scale, and CAPS were significantly higher in the PTSD group. The PTSD group showed a significant difference on the Fazekas scale compared to the trauma-exposed group without PTSD (periventricular white matter, p=0.001; deep white matter, p=0.008). After adjusting for age, smoking and comorbidity, WMH was higher in the PTSD group than in the trauma exposed group (periventricular white matter, p<0.001; deep white matter, p=0.006).
Conclusion: The results suggests that there may be an association between PTSD and WMH as well as stressful events
|
|
|
KEYWORD
|
|
|
Post-traumatic stress disorder, White matter hyperintensity, Veterans
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|